Multiple myeloma: a clinical case report
Mieloma múltiplo: relato de caso clínico
Palavras-chave:
malignant neoplasms, plasmacytoma, multiple myelomaResumo
Objective: To report and discuss the clinical and histopathological findings of a case of multiple myeloma in the jaw region. Case Report: A 58 year old female patient came to UNIPAR Dentistry School complaining of "increased volume on the left side of the face". On physical examination it was observed intact mucosa with buccal cortical expansion in the region of the teeth 34/35/36 and asymptomatic. Radiographic examination revealed a radiolucent area approximately 25 mm in diameter. An incisional biopsy was performed and the histopathological diagnosis was suggestive of plasmacytoma/multiple myeloma, and after finding other lesions it was confirmed as multiple myeloma. The patient was then referred to a hematologist who, together with the oncologist, established the treatment. Conclusion: Although treatment is a medical responsibility, the dental surgeon has an important role in the early diagnosis of this disease, since some of its first clinical and radiographic findings are related to the maxillomandibular complex.
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Referências
ACQUAH, Michael E. et al. Presentation and survival of multiple myeloma patients in Ghana: a review of 9 cases. Ghana medical journal, v. 53, n. 1, p. 52-58, 2019.
BITTENCOURT, Rosane et al. Talidomida e mieloma múltiplo: verificação dos efeitos terapêuticos através de parâmetros clínico e laboratoriais. Revista Brasileira de Hematologia e Hemoterapia, v. 26, p. 245-255, 2004.
COELHO, Caio Santiago Ferreira et al. Relato de caso: mieloma múltiplo diagnosticado em paciente jovem e com eletroforese de proteínas normal. Revista Eletrônica Acervo Científico, v. 11, p. e3420-e3420, 2020.
DOMINGOS, Nara Régia da Silva et al. Recidiva de mieloma múltiplo em mandíbula mimetizando lesão endodôntica: relato de caso. Revista Portuguesa de Estomatologia, Medicina Dentária e Cirurgia Maxilofacial, v. 61, n. 2, p. 86-90, 2020.
DOS SANTOS, Raissa Stefany Batista et al. Mieloma múltiplo diagnosticado em paciente de um hemocentro do nordeste brasileiro: estudo de caso. Revista Eletrônica Acervo Saúde, v. 15, n. 2, p. e9733-e9733, 2022.
FOTIOU, Despina et al. A review of the venous thrombotic issues associated with multiple myeloma. Expert review of hematology, v. 9, n. 7, p. 695-706, 2016.
LASKARIS, George. Atlas colorido de doenças da boca. Artmed, 2004.
MELO, Andréia C. et al. Osteonecrose da mandíbula em paciente portador de mieloma múltiplo: patologia secundária ao uso do pamidronato. Revista Brasileira de hematologia e hemoterapia, v. 27, p. 221-222, 2005.
MILANI, Lucas Zanetti; FERNANDES, Mário Sérgio. Abordagem inicial ao paciente com suspeita de mieloma múltiplo. Acta médica, v. 39, n. 2, p. 29-36, 2018.
NEVILLE BW, DAMM DD, WHITE DK. Atlas Patologia Oral & Maxilofacial. 2 ed. Rio de Janeiro: Guanabara Koogan; 2004. p. 236.
SALEMA, Caroline Luzes Zito; DE CARVALHO, Claudemir. Diagnósticos, tratamentos e prognósticos do mieloma múltiplo. Revista Ciência e Saúde On-line, v. 4, n. 1, 2019.
SIEGEL, R. L.; MILLER, K. D.; FUCHS, H. E. Jemal a. cancer statistics, 2020. Ca Cancer J Clin, v. 70, n. 1, p. 7-30, 2020.
SOUSA, Jacqueline Holanda de et al. Protocolo de tratamento do mieloma múltiplo: serviço de hematologia Hospital Universitário Walter Cantídio, abril-2019. 2020.
SOUZA, Daniella Abbruzzini Ferreira de et al. Mieloma múltiplo com plasmocitomas cutâneos. Anais brasileiros de dermatologia, v. 79, p. 581-585, 2004.
VO, Manh-Cuong et al. Cellular immunotherapy in multiple myeloma. The Korean journal of internal medicine, v. 34, n. 5, p. 954-965, 2019.
