Bioinformatics approaches to explore the discovery of new plant-derived drugs: a brief review
Palavras-chave:
Computational analyses, Virtual screening, Molecular docking, PhytochemistryResumo
This article reviews the role of bioinformatics approaches in drug discovery from medicinal plants, with an emphasis on the use of computational tools for the analysis of genomic, proteomic, and metabolomic data. These techniques facilitate the screening of bioactive compounds with therapeutic potential, optimizing the identification of new drug candidates. Methods such as molecular docking and molecular modeling are fundamental for predicting interactions between ligands and target proteins, supporting the rational development of new drugs. The article also discusses the importance of metabolic pathway analyses and molecular interaction networks in the selection of promising plant species. The combination of bioinformatics and phytochemistry emerges as a crucial strategy to accelerate the drug discovery process, reducing both costs and development time, with great potential to enhance medical therapies.
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