Resfriamento de couro cabeludo para prevenção de alopecia induzida por quimioterapia: Estudo descritivo

Autores

DOI:

https://doi.org/10.53660/CLM-387-505

Palavras-chave:

Oncologia, Quimioterapia, Alopecia, Resfriamento de couro cabeludo, Enfermagem

Resumo

Objetivo: Descrever o efeito do resfriamento de couro cabeludo na prevenção de alopecia induzida por quimioterapia e os efeitos adversos dessa intervenção. Método: Estudo descritivo. Foram incluídos pacientes que receberam resfriamento de couro cabeludo para prevenção de alopecia induzida por quimioterapia. Os dados foram obtidos do prontuário eletrônico dos pacientes. Perda capilar menor que 50% foi considerada sucesso da intervenção. Foi realizada análise descritiva para todas as variáveis. Resultados: Foram incluídas 199 mulheres, com idade média de 54 anos, a maioria com câncer de mama. A média de sessões de resfriamento de couro cabeludo foi de 8,24. Prevenção da alopecia foi observada em 66 (85,7%) pacientes que receberam protocolo de quimioterapia com antraciclinas e em 118 (96,7%) sem antraciclinas. Dor no couro cabeludo, foi relatada por 26% dos pacientes após 10 minutos de resfriamento e por 24% após 30 minutos. Cefaleia foi reportada por 11,6% dos pacientes, intolerância ao frio por 23,1% e tontura por 10,6%. Conclusão: O resfriamento de couro cabeludo mostrou-se efetivo para prevenir alopecia induzida por quimioterapia. Protocolos de controle álgico devem ser estabelecidos.

Downloads

Não há dados estatísticos.

Referências

BAJPAI, J.; et al. Randomized controlled trial of scalp cooling for the prevention of chemotherapy induced alopecia. Breast, v. 49, p. 187-193, 2020. Disponível em: https://doi.org/10.1016/j.breast.2019.12.004

CHOI, E.K.; et al. Impact of chemotherapy-induced alopecia distress on body image, psychosocial well-being, and depression in breast cancer patients. Psychooncology, v. 23, n. 10, p. 1103-1110, 2014. Disponível em: https://doi.org/10.1002/pon.3531

CTCAE. Common Terminology Criteria for Adverse Events. Department of Health and Human Services; National Institutes of Health; National Cancer Institute. Version 4.03: May 28, 2009, U.S Disponível em: https://evs.nci.nih.gov/ftp1/CTCAE/CTCAE_4.03/Archive/CTCAE_4.0_2009-05-29_QuickReference_8.5x11.pdf

DUNILL, C. J.; et al. A Clinical and Biological Guide for Understanding Chemotherapy- Induced Alopecia and Its Prevention. Oncologist, v. 23, p. 84-96, 2018. Disponível em: https://doi.org/10.1634/theoncologist.2017-0263

FREITES-MARTINEZ, A.; et al. Assessment of Quality of Life and Treatment Outcomes of Patients With Persistent Postchemotherapy Alopecia. JAMA Dermatol, v. 155, n. 6, p. 724-728, 2019. Disponível em: https://doi.org/10.1001/jamadermatol.2018.5071

GIANOTTI, E.; et al. Scalp Cooling in Daily Clinical Practice for Breast Cancer Patients Undergoing Curative Chemotherapy: A Multicenter Interventional Study. Asia Pac J Oncol Nurs, v. 6, p. 277-282, 2019. Disponível em: https://doi.org/10.4103/apjon.apjon_4_19

GIARRATANO, T.; et al. Use of scalp cooling device to prevent alopecia for early breast câncer patients receiving chemotherapy: a prospective study. Breast J, v. 26, n. 7, p. 1296-1301, 2020. Disponível em: https://doi.org/10.1111/tbj.13711

HESKETH, P.J.; et al. Chemotherapy-induced alopecia: psychosocial impact and therapeutic approaches. Support Care Cancer, v. 12, p. 543-549, 2004. Disponível em: https://doi.org/10.1007/s00520-003-0562-5

KINOSHITA, T.; et al. Efficacy of Scalp Cooling in Preventing and Recovering From Chemotherapy-Induced Alopecia in Breast Cancer Patients: The HOPE Study. Front Oncol, v. 9, p. 733, 2019. Disponível em: https://dx.doi.org/10.3389%2Ffonc.2019.00733

MUNZONE, E.; et al. Preventing chemotherapy-induced alopecia: a prospective clinical trial on the efficacy and safety of a scalp-cooling system in early breast cancer patients treated with anthracyclines. Br J Cancer, v. 121, n. 4, p. 325-331, 2019. Disponível em: https://doi.org/10.1038/s41416-019-0520-8

MUSTOE, M.M.; et al. The DigniCap Scalp Cooling System and its use in the treatment of chemotherapy-induced alopecia. Future Oncol, v. 14, n. 24, p. 2461-2469, 2018. Disponível em: https://doi.org/10.2217/fon-2018-0178

NANGIA, J.; et al. Effect of a scalp cooling device on alopecia in women undergoing chemotherapy for breast cancer: The SCALP randomized clinical trial. JAMA, v. 317, 596-605, 2017. Disponível em: https://doi.org/10.1001/jama.2016.20939

ORLANDO, L.; et al. Final results of a prospective study of scalp cooling in preventing chemotherapy-induced alopecia. Future Oncol, v. 15, n. 29, p. 3337–3344, 2019. Disponível em: https://doi.org/10.2217/fon-2019-0066

PAUS, R.; et al. Pathobiology of chemotherapy-induced hair loss. Lancet Oncol, v.14, p. e50–59, 2013. Disponível em: https://doi.org/10.1016/s1470-2045(12)70553-3

ROSS, M.; FISCHER-CARTLIDGE, E. Scalp Cooling: A Literature Review of Efficacy, Safety, and Tolerability for Chemotherapy-Induced Alopecia. Clin J Oncol Nurs, v. 21, n. 2, p. 226-233, 2017. Disponível em: https://doi.org/10.1188/17.cjon.226-233

ROSSI, A.; et al. Chemotherapy-induced alopecia management: clinical experience and practical advice. J Cosmet Dermatol, v. 16, n. 4, p. 537–541, 2017. Disponível em: https://doi.org/10.1111/jocd.12308

RUBIO-GONZALEZ, B.; et al. Pathogenesis and treatment options for chemotherapy-induced alopecia: a systematic review. Int J Dermatol, v. 57, n. 12, p. 1417-1424, 2018. Disponível em: https://doi.org/10.1111/ijd.13906

RUGO, H. S.; VOIGT, J. Scalp hypothermia for preventing alopecia during chemotherapy. A Systematic review and meta-analysis of randomized controlled trials. Clinical Breast Cancer, v. 18, n. 1, p. 19–28, 2018. Disponível em: https://doi.org/10.1016/j.clbc.2017.07.012

RUGO, H.S.; et al. Association Between Use of a Scalp Cooling Device and Alopecia After Chemotherapy for Breast Cancer. JAMA, v.317, n. 6, p. 606–614, 2017. Disponível em: https://doi.org/10.1001/jama.2016.21038

SAAD, M.; et al. The efficacy and tolerability of scalp cooling in preventing chemotherapy-induced alopecia in patients with breast cancer receiving anthracycline and taxane-based chemotherapy in an Asian setting. Indian J Cancer, v. 55, p. 157-161, 2018. Disponível em: https://doi.org/10.4103/ijc.ijc_581_17

SHAH, V.V.; et al. Scalp hypothermia as a preventative measure for chemotherapy-induced alopecia: a review of controlled clinical trials. J Eur Acad Dermatol Venereol, v. 32, n. 5, p. 720-734, 2018. Disponível em: https://doi.org/10.1111/jdv.14612

SHIN, H.; et al. Efficacy of interventions for prevention of chemotherapy-induced alopecia: A systematic review and meta-analysis. Int J Cancer, v. 136, p. E442–454, 2015. Disponível em: https://doi.org/10.1002/ijc.29115

SMETANAY, K.; et al. COOLHAIR: a prospective randomized trial to investigate the efficacy and tolerability of scalp cooling in patients undergoing (neo)adjuvant chemotherapy for early breast cancer. Breast Cancer Res Treat, v. 173, n. 1, p. 135-143, 2019. Disponível em: https://doi.org/10.1007/s10549-018-4983-8

VASCONCELOS, I.; WIESSKE, A.; SCHOENEGG, W. Scalp cooling successfully prevents alopecia in breast cancer patients undergoing anthracycline/taxane-based chemotherapy. Breast, v. 40, p. 1-3, 2018. Disponível em: https://doi.org/10.1016/j.breast.2018.04.012

WATANABE, T.; et al. A multicenter survey of temporal changes in chemotherapy induced hair loss in breast cancer patients. PLoS ONE, v. 14, n. 1, p. e0208118, 2019. Disponível em: https://doi.org/10.1371/journal.pone.0208118

YEAGER, C.E.; OLSEN, E.A. Treatment of chemotherapy-induced alopecia. Dermatol Ther, v. 24, p. 432-442, 2011. Disponível em: https://doi.org/10.1111/j.1529-8019.2011.01430.x

Publicado

2022-09-01

Como Citar

Alves, L. . ., Aguiar, B., Gomes, I., Fagundes, J., Figueiredo, E., Vasques, C., & Reis, P. (2022). Resfriamento de couro cabeludo para prevenção de alopecia induzida por quimioterapia: Estudo descritivo . Concilium, 22(5), 79–91. https://doi.org/10.53660/CLM-387-505

Edição

Seção

Articles