Copaiba oil on dentistry: a scoping review
Óleo de copaíba na odontologia:uma revisão de escopo
Palavras-chave:
Phytotheraphy;, Copaifera, Biomaterials;, Dental Materials.Resumo
Copaiba oil is a natural product commonly employed in traditional medicine due to qualities as anti-inflammatory and antimicrobial mainly. On dentistry, studies have focused on the use of copaiba in cavity varnishes, endodontic cements, bacterial biofilm control and even in the composition of local anesthetics. The aim of this study was to investigate on the use of copaiba oil within dental specialties. The search was conducted on databases using the primary keywords ‘Copaifera’ and ‘Dentistry’ resulting in 687 studies. Was observed that Copaifera multijuga was the most prevalent species in the evaluated articles, endodontics was the most presente dental specialty in publications. Antimicrobial tests and biocompatibility tests was most prevalents. Based on the results of this study, despite the limited number of evaluated works, it can be concluded that over the years, copaiba has been increasingly used in dentistry, yielding promising results such as the development of new bioproducts that combine copaiba's pharmacological characteristics without compromising the necessary physical attributes for clinical use.
Downloads
Referências
Abrão, F., Alves, J. A., Andrade, G., de Oliveira, P. F., Ambrósio, S. R., Veneziani, R. C. S., Tavares, D. C., Bastos, J. K., & Martins, C. H. G. 2018. Antibacterial Effect of Copaifera duckei Dwyer Oleoresin and Its Main Diterpenes against Oral Pathogens and Their Cytotoxic Effect. Frontiers in microbiology, 9, 201.
Alvarenga, M. O. P., Bittencourt, L. O., Mendes, P. F. S., Ribeiro, J. T., Lameira, O. A., Monteiro, M. C., Barboza, C. A. G., Martins, M. D., & Lima, R. R. 2020. Safety and Effectiveness of Copaiba Oleoresin (C. reticulata Ducke) on Inflammation and Tissue Repair of Oral Wounds in Rats. International journal of molecular sciences, 21(10), 3568.
Araújo, E. A. M., Lima, G. R., Dos Santos de Melo, L. A., de Sousa, L. B., de Vasconcellos, M. C., Conde, N. C. O., Toda, C., Hanan, S. A., Alves Filho, A. O., & Bandeira, M. F. C. L. 2021. Effect of a Copaiba Oil-Based Dental Biomodifier on the Inhibition of Metalloproteinase in Adhesive Restoration. Advances in pharmacological and pharmaceutical sciences, 2021, 8840570.
Bandeira, M. F., Lima, G. R., Lopes, P. P., Toda, C., Venâncio, G. N., Lima, G. A., de Vasconcellos, M. C., Martins, L. M., Sampaio, F. C., & Conde, N. C. 2016. Dentin Cleaning Ability of an Amazon Bioactive: Evaluation by Scanning Electron Microscopy. The open dentistry journal, 10, 182–187.
Bandeira, M. F. C. L., Freitas, A. L., Menezes, M. S. C., Silva, J. D. S., Sombra, G. A. D., Araújo, E. A. M., Toda, C., Moreschi, A. R. C., & Conde, N. C. O. 2020. Adhesive resistance of a copaiba oil-based dentin biomodifier. Brazilian oral research, 34, e001.
Bari, C. C. D., Sampaio, F., Conde, N., Moura, L., Veiga Júnior, V., Barbosa, G., Vasconcellos, M., Toda, C., Venâncio, G., & Bandeira, M. F.. 2016. Amazon emulsions as cavity cleansers: antibacterial activity, cytotoxicity and changes in human tooth color. Revista Brasileira De Farmacognosia, 26(4), 497–501.
Cavalcante, A. de M., da Silva, J. R., Oliveira, L. C. L., da Silva, M. A. B., Ribeiro Junior, K. A. L., & de Santana, A. E. G. 2021. Analysis of the antimicrobial action of copaiba oil and endodontic substances against anaerobic bacteria. Scientific Research and Essays, 16(1), 1-7.
Couto, R.S.D.; Rodrigues, M.F.S.D.; Ferreira, L.S.; Diniz, I.M.A.; Silva, F.d.S.; Lopez, T.C.C.; Lima, R.R.; Marques, M.M. 2020.Evaluation of Resin-Based Material Containing Copaiba Oleoresin (Copaifera Reticulata Ducke): Biological Effects on the Human Dental Pulp Stem Cells. Biomolecules, 10, 972.
da S Moraes, T., Leandro, L. F., de O Silva, L., Santiago, M. B., Souza, A. B., Furtado, R. A., Tavares, D. C., Veneziani, R. C., Ambrósio, S. R., Bastos, J. K., & Martins, C. H. 2016. In vitro Evaluation of Copaifera oblongifolia Oleoresin Against Bacteria Causing Oral Infections and Assessment of Its Cytotoxic Potential. Current pharmaceutical biotechnology, 17(10), 894–904.
Dias-da-Silva, M. A., Pereira, A. C., Marin, M. C., & Salgado, M. A. 2013. The influence of topic and systemic administration of copaiba oil on the alveolar wound healing after tooth extraction in rats. Journal of clinical and experimental dentistry, 5(4), e169–e173.
Dos Santos, V. R. N., Motta, J. V. D. S., Frazão, D. R., Ferreira, R. O., Souza-Monteiro, D., Baia-da-Silva, D. C., Mendes, P. F. S., Bittencourt, L. O., de Moura, J. D. M., Lameira, O. A., Balbinot, G. S., Collares, F. M., Rösing, C. K., & Lima, R. R. 2022. Biological Activity of Copaiba in Damage to the Alveolar Bone in a Model of Periodontitis Induced in Rats. Molecules (Basel, Switzerland), 27(19), 6255.
Dos Santos, A. C. M., Oliveira, V. C., Macedo, A. P., Bastos, J. K., Ogasawara, M. S., Watanabe, E., Chaguri, I. M., Silva-Lovato, C. H., & Paranhos, H. F. O. 2021. Effectiveness of Oil-Based Denture Dentifrices-Organoleptic Characteristics, Physicochemical Properties and Antimicrobial Action. Antibiotics (Basel, Switzerland), 10(7), 813.
Galazi, D.R., Brianezzi, L.F., Góes, A.R.C.G., Mondelli, R.F.L., Ishikiriama, A., Ishikiriama, S.K. 2015.Influence of temporary cement in the tensile strength of full crowns cemented with resin cement. Brasilian Dental Science,18 (3):52-58.
Garcia, L., Cristiane, S., Wilson, M., Soraya, M., Lopes, R. A., Mônica, R., & de Freitas, O. (2011). Biocompatibility assessment of pastes containing Copaiba oilresin, propolis, and calcium hydroxide in the subcutaneous tissue of rats. Journal of conservative dentistry : JCD, 14(2), 108–112
Garrido, A. D., Lia, R. C., França, S. C., da Silva, J. F., Astolfi-Filho, S., & Sousa-Neto, M. D. 2010. Laboratory evaluation of the physicochemical properties of a new root canal sealer based on Copaifera multijuga oil-resin. International endodontic journal, 43(4), 283–291.
Garrido, A. D., de Cara, S. P., Marques, M. M., Sponchiado, E. C., Jr, Garcia, L.daF., & de Sousa-Neto, M. D. 2015. Cytotoxicity evaluation of a copaiba oil-based root canal sealer compared to three commonly used sealers in endodontics. Dental research journal, 12(2), 121–126.
Gomes, L., Lima , G., Mota, A. L., Passos, V., Bandeira, M. F., Conde, N. ., & Toda, C. 2023. Influence of Copaifera multijuga hayne oil-based emulsion on the stability of the dentin matrix: Influência da emulsão à base de óleo de Copaifera multijuga hayne na estabilidade da matriz dentinária. Concilium, 23(3), 560–577.
Lima, R. V., Esmeraldo, M. R., de Carvalho, M. G., de Oliveira, P. T., de Carvalho, R. A., da Silva, F. L., Jr, & de Brito Costa, E. M. 2011. Pulp repair after pulpotomy using different pulp capping agents: a comparative histologic analysis. Pediatric dentistry, 33(1), 14–18.
Lima, C.C., Souza, T.P., Carvalho-Guimarães, F.B., Freitas, D.S., Conde, N.O.,Cangiani, M.B., Correr, A.B., Toda, C. Tensile strenght of a dental cement based on copaíba oil-resin. 2023.Concilium 23(3), 119-130.
Moraes, T. D. S., Leandro, L. F., Santiago, M. B., de Oliveira Silva, L., Bianchi, T. C., Veneziani, R. C. S., Ambrósio, S. R., Ramos, S. B., Bastos, J. K., & Martins, C. H. G. 2020. Assessment of the antibacterial, antivirulence, and action mechanism of Copaifera pubiflora oleoresin and isolated compounds against oral bacteria. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 129, 110467.
Musale, P. K., & Soni, A. S. 2016. Clinical Pulpotomy Trial of Copaifera Langsdorffii Oil Resin Versus Formocresol and White Mineral Trioxide Aggregate in Primary Teeth. Pediatric dentistry, 38(2), 5–12.
Pereira, S. L., Barros, C. S., Salgado, T. D., Filho, V. P., & Costa, F. N. 2010. Limited benefit of copaifera oil on gingivitis progression in humans. The journal of contemporary dental practice, 11(1), E057–E64.
Perfecto, D.R., Luna, A.C. 2014. Actividad antibacteriana de Copaifera reticulata “Copaiba” sobre Porphyromonas gingivalis aisladas de pacientes con periodontitis. Odontología Sanmarquina. 17. 7. 10.15381/os.v17i1.9721.
Pieri, F. A., Mussi, M. C. M., Fiorini, J. E., Moreira, M. A. S., & Schneedorf, J. M.. 2012. Bacteriostatic effect of copaiba oil (Copaifera officinalis) against Streptococcus mutans. Brazilian Dental Journal, 23(1), 36–38.
Reiznautt, C. M., Ribeiro, J. S., Kreps, E., da Rosa, W. L. O., de Lacerda, H., Peralta, S. L., Bottino, M. C., & Lund, R. G. 2021. Development and properties of endodontic resin sealers with natural oils. Journal of dentistry, 104, 103538.
Rosa, P. C., Mancini, M. N., Camargo, S. E., Garrido, A. D., Camargo, C. H., & Rode, S.deM. 2010. Dimensional alterations and solubility of new endodontic sealers. Brazilian dental journal, 21(4), 301–304.
Silva, P. F., Brito, M. V., Pontes, F. S., Ramos, S. R., Mendes, L. C., & Oliveira, L. C. 2015. Copaiba oil effect on experimental jaw defect in Wistar rats. Acta cirurgica brasileira, 30(2), 120–126.
Silva, G. O., Cavalcanti, B. N., Oliveira, T. R., Bin, C. V., Camargo, S. E., & Camargo, C. H. 2016. Cytotoxicity and genotoxicity of natural resin-based experimental endodontic sealers. Clinical oral investigations, 20(4), 815–819.
Silva, S., Alves, N., Silva, P., Vieira, T., Maciel, P., Castellano, L. R., Bonan, P., Velozo, C., & Albuquerque, D. 2019. Antibacterial Activity of Rosmarinus officinalis, Zingiber officinale, Citrus aurantium bergamia, and Copaifera officinalis Alone and in Combination with Calcium Hydroxide against Enterococcus faecalis. BioMed research international, 2019, 8129439.
Simões, C. A., Conde, N. C., Venâncio, G. N., Milério, P. S., Bandeira, M. F., & da Veiga Júnior, V. F.2016. Antibacterial Activity of Copaiba Oil Gel on Dental Biofilm. The open dentistry journal, 10, 188–195.
Teixeira, F. B., de Brito Silva, R., Lameira, O. A., Webber, L. P., D'Almeida Couto, R. S., Martins, M. D., & Lima, R. R. 2017. Copaiba oil-resin (Copaifera reticulata Ducke) modulates the inflammation in a model of injury to rats' tongues. BMC complementary and alternative medicine, 17(1), 313.
Valadas, L. A. R., Gurgel, M. F., Mororó, J. M., Fonseca, S. G. D. C., Fonteles, C. S. R., de Carvalho, C. B. M., Fechine, F. V., Rodrigues Neto, E. M., de França Fonteles, M. M., Chagas, F. O., Lobo, P. L. D., & Bandeira, M. A. M. 2019. Dose-response evaluation of a copaiba-containing varnish against streptococcus mutans in vivo. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 27(3), 363–367.
Valadas, L. A. R., Lobo, P. L. D., Fonseca, S. G. D. C., Fechine, F. V., Rodrigues Neto, E. M., Fonteles, M. M. F., de Aguiar Trévia, L. R., Vasconcelos, H. L. P., Lima, S. M. D. S., Lotif, M. A. L., Fernandes, A. M. B., & Bandeira, M. A. M. 2021. Clinical and Antimicrobial Evaluation of Copaifera langsdorffii Desf. Dental Varnish in Children: A Clinical Study. Evidence-based complementary and alternative medicine : eCAM, 2021, 6647849.
Vasconcelos, K. R. F., Veiga Junior, V. F. da ., Rocha, W. C., & Bandeira, M. F. C. L..2008. Avaliação in vitro da atividade antibacteriana de um cimento odontológico à base de óleo-resina de Copaifera multijuga Hayne. Revista Brasileira De Farmacognosia, 18, 733–738.
Veiga, V. F., Jr, Zunino, L., Calixto, J. B., Patitucci, M. L., & Pinto, A. C. 2001. Phytochemical and antioedematogenic studies of commercial copaiba oils available in Brazil. Phytotherapy research : PTR, 15(6), 476–480.
Wagner, V. P., Webber, L. P., Ortiz, L., Rados, P. V., Meurer, L., Lameira, O. A., Lima, R. R., & Martins, M. D. 2017. Effects of Copaiba Oil Topical Administration on Oral Wound Healing. Phytotherapy research : PTR, 31(8), 1283–1288.
