Micronuclei in buccal mucosa cells of smoking university students: a genotoxicity study

Autores

Thais Larissa Bruschi Universidade Federal da Fronteira Sul - Campus Realeza/Pr. https://orcid.org/0009-0008-7946-6407
Gisele Arruda Universidade Estadual do Oeste do Paraná - Unioeste. https://orcid.org/0000-0002-5690-2527
Vanessa Silva Retuci Universidade Federal da Fronteira Sul - Campus Realeza/Pr. https://orcid.org/0000-0002-8573-6644
Alexandre Carvalho de Moura Universidade Federal da Fronteira Sul - Campus Realeza/Pr. https://orcid.org/0000-0002-0894-2903
Suzymeire Baroni Universidade Federal da Fronteira Sul - Campus Realeza/Pr. https://orcid.org/0000-0002-0586-3978
Gilza Maria de Souza-Franco Universidade Federal da Fronteira Sul - Campus Realeza/Pr. https://orcid.org/0000-0002-5023-3211
Izabel Aparecida Soares Universidade Federal da Fronteira Sul

Palavras-chave:

Micronucleus;, Nuclear alterations;, University students.

Resumo

This study explores and contrasts the genotoxic effects of conventional and electronic cigarette use on the buccal mucosa cells of university students, using the micronucleus test. We conducted field research with qualitative and quantitative methods, involving 28 participants over 18 years old, distributed into four groups: conventional cigarette users, electronic cigarette users, dual users, and non-smokers. Participants were selected based on specific criteria, and demographic and motivational information was obtained through questionnaires. Buccal mucosa samples were collected according to standard cytological methods, analyzing 500 cells per participant. Analysis revealed statistically significant differences in micronucleus incidence and cellular alterations between smoker and non-smoker groups. These findings underscore the need for stricter tobacco control policies and pave the way for future research on tobacco genotoxicity.

Biografia do Autor

Thais Larissa Bruschi, Universidade Federal da Fronteira Sul - Campus Realeza/Pr.

Acadêmica do Curso de Ciências Biológicas - Campus Realeza/Pr.

Gisele Arruda, Universidade Estadual do Oeste do Paraná - Unioeste.

Docente e pesquisadora na Universidade Estadual do Oeste do Paraná - Campus Francisco Beltrão.

Vanessa Silva Retuci, Universidade Federal da Fronteira Sul - Campus Realeza/Pr.

Docente e pesquisadora na Universidade Federal da Fronteira Sul - Campus Realeza/Pr.

Alexandre Carvalho de Moura, Universidade Federal da Fronteira Sul - Campus Realeza/Pr.

Docente e pesquisador na Universidade Federal da Fronteira Sul - Campus Realeza/Pr.

Suzymeire Baroni, Universidade Federal da Fronteira Sul - Campus Realeza/Pr.

Docente e pesquisadora na Universidade Federal da Fronteira Sul - Campus Cerro Largo/RS.

Gilza Maria de Souza-Franco, Universidade Federal da Fronteira Sul - Campus Realeza/Pr.

Docente e pesquisadora na Universidade Federal da Fronteira Sul - Campus Realeza/Pr.

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Micronuclei in buccal mucosa cells of smoking university students: a genotoxicity study

Micronúcleos em células da mucosa bucal de universitários fumantes: um estudo de genotoxicidade