Profile of transfusions carried out in the medical clinic and intensive care units of a hospital in the central hinterland of ceará
Perfil das transfusões realizadas nas unidades de clínica médica e terapia intensiva de um hospital do sertão central do ceará
Palavras-chave:
Transfusion, Blood bank, EpidemiologyResumo
Objective: This study aimed to describe the profile of transfusions carried out at the Hospital Regional do Sertão Central (HRSC) in 2022 in the medical clinic sector and intensive care unit (ICU). Background: Transfusion of blood components is a procedure with significant risks, which is why the World Health Organization (WHO) encourages the development of programs for the proper management of blood components through Patient Blood Management strategies, optimizing the use of this products. In this context, the transfusion agency at HRSC collects information and generates indicators to assess the level of adherence to its safety protocol. Methods/Materials: Data of transfusions in adults were collected by recording quality indicators of the HRSC transfusion agency and then a retrospective, descriptive, and quantitative analysis were conducted. Results: This study analyzed 1072 transfusions, with 53.3% occurring in men and 46.7% in women, with a mean age of 42 years. The ICU requested 79.1% of the transfusions. Symptomatic anemia and bleeding were the cause. Concentrated red blood cells (73%) were most required, 49.6% of which were O+. In terms of criticality, 54% of the requests were urgent. Sixteen adverse reactions notifications were observed. Conclusion: Analysis of the transfusions made it possible to identify and describe the characteristics of the transfusion process in a tertiary referral hospital in a city in the interior of Ceará. The data survey showed that the team maintained good levels of adherence to the transfusion indication protocol but with possible underreporting of transfusion reactions.
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Referências
AABB - Association for the Advancement of Blood & Biotherapies. Technical Manual. 20 ed. Bethesda. 2020.
ARRUDA, A. B. de L. et al. Perfil dos doadores de sangue de primeira vez de um serviço de hemoterapia. Brazilian Journal of Health Review, v. 2, n. 6, p. 5135–5147, 2019. DOI: 10.34119/bjhrv2n6-020. Available in: https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/4478.
ACKFELD, T.; SCHMUTZ, T; GUECHI, Y.; LE TERRIER, C. Blood Transfusion Reactions - A Comprehensive Review of the Literature including a Swiss Perspective. J Clin Med. 2022 May 19;11(10):2859. doi: 10.3390/jcm11102859. PMID: 35628985; PMCID: PMC9144124.
BIAGINI, S. (Org.). Manual do Programa de Bolsa de Sangue. São Paulo: PROSANGUE, 2021. Available in: https://www.prosangue.sp.gov.br/uploads/arquivos/Manual%20PBM%202021%20Final.pdf.
BRASIL. Agência Nacional de Vigilância Sanitária (ANVISA) (ed.). Boletim de Hemovigilância: Número 07. In: Publicações de Hemovigilância. Brasil. 2015. Available in: https://www.gov.br/anvisa/pt-br/centraisdeconteudo/publicacoes/monitoramento/hemovigilancia. Acesso em: 1 fev. 2024.
BRASIL. Manual para o Sistema Nacional de Hemovigilância no Brasil. ANVISA. Brasília. 2022.
BRITO, M. et al. Implantação de indicadores de desempenho nas agências transfusionais do hemocentro coordenador de Fortaleza como ferramenta de gestão. Hematology, Transfusion and Cell Therapy, v. 44, p. 538-539, out. 2022. Elsevier BV. http://dx.doi.org/10.1016/j.htct.2022.09.920.
BEIGUELMAN, B. Os sistemas sangüíneos eritrocitários. FUNPEC Editora, Ribeirão Preto, SP, 2003.
CEARÁ. Hemoce realiza evento online sobre hemovigilância em parceria com Ebserh. [S. l.]: Assessoria de Comunicação do Hemoce, 7 dez. 2021. Available in: https://www.hemoce.ce.gov.br/2021/12/07/hemoce-realiza-evento-online-sobre-hemovigilancia-em-parceira-com-ebserh/.
KARAFIN, M.S. et al. Demographic and epidemiologic characterization of transfusion recipients from four US regions: evidence from the REDS-III recipient database. Transfusion, v. 57, p. 2903-2913, 2018. https://doi.org/10.1111/trf.14370.
MUELLER, M.M. et al. Patient Blood Management: Recommendations From the 2018 Frankfurt Consensus Conference. JAMA, v. 321, n. 10, p. 983–997, 2019. doi:10.1001/jama.2019.0554.
QUINTANA-DIAZ, M. et al. Epidemiology of blood transfusion in the Spanish Critical Care Units: «Transfusion Day». Medicina Intensiva (English Edition), v. 46, n. 3, p. 123-131, 2022. https://doi.org/10.1016/j.medine.2021.12.006.
RAASVELD, S.J. et al. Red Blood Cell Transfusion in the Intensive Care Unit. JAMA, v. 330, n. 19, p. 1852-1861, 2023. doi: 10.1001/jama.2023.20737.
SHARIF, M. et al. Blood Component Transfusion in a Tertiary Care Hospital. Indian J Pediatr, v. 87, p. 339–344, 2020. https://doi.org/10.1007/s12098-020-03186-2.
DE SOUZA, D. A.; SILVA, F. G. E.; COSTA, P. J. M. S. Critical evaluation of justifications for the transfusion of red blood cells: the reality of a government emergency hospital. Revista Brasileira de Hematologia e Hemoterapia, v. 35, n. 4, p. 263–267, 2013.
TORMEY, C.A.; HENDRICKSON, J.E. Transfusion-related red blood cell alloantibodies: induction and consequences. Blood, 2019. Available in: http://doi.org/10.1182/blood-2018-08-833962.
GELAW, Y.; WOLDU, B.; MELKU, M. Proportion of Acute Transfusion Reaction and Associated Factors Among Adult Transfused Patients at Felege Hiwot Compressive Referral Hospital, Bahir Dar, Northwest Ethiopia: A Cross-Sectional Study. J Blood Med. 2020. doi: 10.2147/JBM.S250653.