Risk factors for the development of candidemia in patients with positive urine surveillance culture for Candida spp.

Fatores de risco para o desenvolvimento de candidemia em pacientes com cultura de vigilância de urina positiva para Candida spp.

Autores

Isabela Cristina Marocchio Vasconcellos Universidade do Oeste Paulista, Brasil
Camila Karoline Oliveira Silva Universidade do Oeste Paulista, Brasil
Laura Roberta Reis de Oliveira Universidade do Oeste Paulista, Brasil
Matheus Luiz de Oliveira Raymundi Universidade do Oeste Paulista, Brasil
Kelly Cristina Barzan Universidade do Oeste Paulista, Brasil
Eliana Peresi-Lordelo Universidade do Oeste Paulista - Unoeste
Daniela Vanessa Moris Universidade do Oeste Paulista

Palavras-chave:

Candida spp. infection, Candidemia, Risk Factors, Intensive Care Unit

Resumo

The objective of the study was to characterize candiduria in patients admitted to a tertiary hospital and establish the risk factors associated with the development of candidemia. To this end, a laboratory and clinical surveillance study was carried out with samples of Candida spp. previously isolated from urine surveillance cultures of patients admitted to the Intensive Care Unit, during the period from 2019 to 2020. It was demonstrated that the incidence of candidemia in patients with positive urine cultures for Candida spp. it was 17.7 per 1000 admissions and 80% of patients who developed candidemia died. The chance of developing candidemia was eight times greater in patients who had diseases of the digestive system that caused hospitalization and 26 times greater in those who had Coronary Artery Disease (CAD), compared to patients who did not have the comorbidity. We concluded that the possibility of developing candidemia from candiduria is 4.5%, however, the onset of candidemia, regardless of the source, worsens the patient's prognosis.

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