Coinfections associated with COVID-19 in patients admitted to an adult ICU in the interior of the Amazon

Coinfecções associadas a COVID-19 em pacientes internados em uma UTI Adulto no interior da Amazônia

Autores

  • Irinéia de Oliveira Bacelar Simplício UEPA/UAM
  • Teresa Victória Silva
  • Ana Gabriela Santos
  • Jessica Priscila Soares
  • Jociléia Bezerra
  • Antônia Irisley Blandes
  • Walten Kleberson Nogueira
  • Monica Karla Vojta Miranda

Palavras-chave:

Coinfection;, SARS-CoV-2;, Intensive Care Unit;

Resumo

Coinfections by SARS-CoV-2 with other microorganisms, such as bacteria, viruses and fungi, is a determining factor that must be considered. Because the early detection of these coinfections can directly interfere with the length of hospitalization and, consequently, mortality. This study aimed to identify the epidemiological profile of patients and coinfections associated with COVID-19 carriers in an adult Intensive Care Unit (ICU) of a hospital in the interior of the Amazon. This is a retrospective, descriptive and documentary study, with a quantitative approach. The data sample was obtained from the Hospital Infection Control Commission (E-CCIH) registration system. 95 medical records of patients with COVID-19 associated with coinfections were analyzed. The prevalence of females was 62.1% and the average age was 58 years, 82.1% were brown and the highest prevalence for high school was 32.6%. Related to the site of infection, the study revealed that Ventilator-Associated Pneumonia (VAP) was the most prevalent condition with 53.7% of cases. Regarding the discharges, 60% were due to death. Coinfections associated with COVID-19 reveal a poor prognosis, worsening in the presence of respiratory system comorbidities.

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Referências

ALOSAIMI, B.; NAEEM, A.; HAMED, M. E.; ALKADI, H. S. et al. Influenza coinfection associated with severity and mortality in patients with COVID-19. J Virol, v. 18, n. 1, p. 1-9, 2021.

ASMARAWATI, T. P.; ROSYID, A. N.; SURYANTORO, S. D.; MAHDI, B. A. et al. The clinical impact of bacterial co-infection among moderate, severe and critically ill COVID-19 patients in the second referral hospital in Surabaya. F1000Res, v. 10, p. 113, 2021.

BOLKER, A.; COE, K.; SMITH, J.; STEVENSON, K et al. Predictors of respiratory bacterial co-infection in patients hospitalized with COVID-19. Diagn Microbiol Infect Dis, 102, n. 1, p. 115558-64, 2022.

CARVALHO, C. D. C.; MARTINS, M.; VIACAVA, F.; PEIXOTO, C. D. P. et al. Pandemia da Covid-19: variação no uso de internações hospitalares nos municípios g100. Saúde em Debate, v. 46, p. 89-105, 2023.

CASTAÑEDA-MÉNDEZ, P.; CABRERA-RUIZ, M. L.; BARRAGÁN-REYES, A.; AGUILAR, E. A. et al. Epidemiologic and Microbiologic Characteristics of Hospital-acquired Infections in Patients with COVID-19 at Intensive Care Unit, Mexico City. Open Forum Infectious Diseases, v. 8, sup. 1, p. S296, 2021.

CURCI, C.; NEGRINI, F.; FERRILLO, M.; BERGONZI, R. et al. Functional outcome after in-hospital rehabilitation in post-intensive care unit COVID-19 patients: findings and clinical implications of a retrospective study of real practice. Eur J Phys Rehabil Med, v. 57, n. 3, p. 443-450, 2021.

SILVA, V. V. A. A covid-19 enquanto questão social: classe, escolaridade e cor da pandemia no Pará. Holos, v. 1, p. 1-14, 2021.

DAVIES-BOLORUNDURO, O. F.; FOWORA, M. A.; AMOO, O. S.; ADENIJI, E. et al. Assessment of respiratory tract bacterial coinfections in SARS-CoV-2 patients with mild or asymptomatic infection in Lagos, Nigéria. Bull Natl Res Cent, v. 46, n. 1, p. 115-23, 2022.

FAZIO, R.; RUISCH, B. C.; MOORE, C. A.; SAMAYOA, J. A. G et al. Social distancing decreases an individual's likelihood of contracting COVID-19. PNAS, v. 118, n. 8, p. 1-5, 2021.

GRASSELLI, G.; SCARAVILLI, V.; MANGIONI, D.; SCUDELLER, L. et al. Hospital-acquired infections in critically ill patients with COVID-19. Peito, v. 160, n. 2, p. 454-465, 2021.

GREGO, R.; PANETTA, V.; DELLA ROCCA, M. T.; DURANTE, A. et al. Prevalence profile of co-infection and antibiotic use among patients with COVID-19. Pathogens, v. 11, n. 11, p. 1250-61, 2022.

Instituto Brasileiro de Geografia e Estatística (IBGE). IBGE - Educa|Jovens. Conheça o Brasil- População Cor ou Raça. Disponível em: https://educa.ibge.gov.br/jovens/conheca-o- brasil/populacao/18319-cor-ou-raca.html. Acesso em: 27 de ago. 2023.

KARUNA, T.; GARG, R.; KUMAR, S.; SINGH, G.; PRASAD, L. et al. Clinical- Epidemic-Microbiological Exprloratory Review Aong COVID-19 Patients With Secondary Infection in Central India. Infect Drug Resist, v. 15, p. 1667-1676, 2022.

LIMA, M.; MILANEZI, J.; SOUSA, C. J. et al. Desigualdades Raciais e Covid-19: o que a pandemia encontra no Brasil? Informativo Desigualdades Raciais e Covid-19. AFRO- CEBRAP, n. 1, p. 1-28, 2020.

MARINHO, F.; TEIXEIRA, R.; MACHADO, H. A.; LIMA, M. et al. Disparidades raciais no excesso de mortalidade em tempos de Covid-19 em São Paulo. Informativos Desigualdades Raciais e Covid19. AFRO-CEBRAP, v. 8, p. 1-23, 2021.

MASCARELLO, K. C.; VIEIRA, A. C. B. C.; SOUZA, A. S. S. D.; MARCARINI, W. D. et al. Hospitalização e morte por COVID-19 e sua relação com determinantes sociais da saúde e morbidades no Espírito Santo: um estudo transversal. Epidemiologia e Serviços de Saúde, v. 30, n. 3, p. 1-12, 2021.

RAWSON, T. M.; WILSON, R. C.; HOLMES, A. Understanding the role of bacterial and fungal infection in COVID-19. Clin. Microbiol. Infect., v. 27, n. 1, p. 9-11, 2021.

RIBEIRO, E. A.; OLIVEIRA, R. A.; GAMA MELO, J. D.; SILVA, G. T. P. et al. Detecção fenotípica de bactérias gram-negativas produtoras de carbapenemases em efluente hospitalar na Amazônia, no estado do Pará, Brasil. Revista EVS, v. 47, n. 1, p. 7939-50, 2020.

SHARIFI, A.; KAVOOSI, F.; HOSSEINI, S. M. J.; MOSAVAT, A. et al. Prevalence of Streptococcus pneumoniae in ventilator-associated pneumonia by real-time PCR. Archives of Clinical Infectious Diseases, v. 14, n. 3, 2019.

SOUTO, X. M. COVID-19: aspectos gerais e implicações globais. Recital-Revista de Educação, Ciência e Tecnologia de Almenara/MG, v. 2, n. 1, p. 12-36, 2020.

TONNERA, I. B.; FINOTTI, L. L. Perfil clínico-epidemiológico de pacientes com COVID-19 internados na unidade de terapia intensiva de um hospital referência do sul catarinense. Negro-Dellacqua: Melissa. 2022. 39p. Trabalho de Conclusão de Curso – Medicina, Universidade Federal de Santa Catarina, Araranguá, 2022.

WORLD HEALTH ORGANIZATION (WHO). An update on SARS-CoV-2 virus mutations & variants. Disponível em: https://www.who.int/docs/default-source/coronaviruse/risk- comms-updates/update47-sars-cov-2-variants.pdf?sfvrsn=f2180835_4. Acesso em: 20 de fevereiro de 2023.

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Publicado

2024-03-11

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Articles