Feline exocrine pancreatic insufficiency: case report
Insuficiência pancreática exócrina em felino: relato de caso
Resumo
Feline Exocrine Pancreatic Insufficiency is a disease where the digestion and absorption of nutrients its impaired due to lacking pancreatic enzymes in the intestine. This study aimed to report a case of EPI in a femeale cat, with five years of age, that presented weight loss, liquid diarrhea, and coat alterations. A hemogram and serum biochemestry (ALT and Creatinine), coproparasitological and abdominal ultrasonography were requested. Due to clinical worsening, test results, hepatomegaly and splenomegaly in the imaging exam, serum mensuration for Free T4, Cobalamin, Folate, Albumin, Globulin, serum GGT, Ionic Calcium, SOdium, Potassium, Total Bilirrubin, Indirect Bilirrubin, Direct Bilirrubin, Urinalyses, urinary creatinin-protein ratio, and especific pancratic lipase were requested, and results did not displayed significative alterations. Hospitalization and fluidotherapy were indicated, along with fenbendazol, probiotic, and cobalamin supplementation treatment, as well as hypoalergeninc diet. After, supplementation with pancreatic enzymes begun in order to verify EPI, resulting in clinical manifestations improvement, and feline trypsinogen was asssesed at 7mcg/L, indicating the correct diagnosis assumption.
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Referências
AUGER, Mylène et al. Abdominal ultrasound and clinicopathologic findings in 22 cats with exocrine pancreatic insufficiency. Journal of Veterinary Internal Medicine, v. 35, n. 6, p. 2652-2661, 2021.
AUGUST, John R. Consultations in Feline Internal Medicine, Volume 6-E-Book. Elsevier Health Sciences, 2009.
BATCHELOR, Daniel J. et al. Prognostic factors in canine exocrine pancreatic insufficiency: prolonged survival is likely if clinical remission is achieved. Journal of veterinary internal medicine, v. 21, n. 1, p. 54-60, 2007.
COSTA DEVOTI, Chiara et al. Exocrine pancreatic insufficiency with concurrent pancreatitis, inflammatory bowel disease and cholangiohepatitis in a cat. Veterinary Record Case Reports, v. 3, n. 1, p. e000237, 2015.
CRIDGE, Harry; WILLIAMS, David A.; BARKO, Patrick C. Exocrine pancreatic insufficiency in dogs and cats. Journal of the American Veterinary Medical Association, v. 1, n. aop, p. 1-10, 2023.
FORMAN, Marnin A. et al. ACVIM consensus statement on pancreatitis in cats. Journal of Veterinary Internal Medicine, v. 35, n. 2, p. 703-723, 2021.
ISAIAH, Anitha et al. The fecal microbiome of dogs with exocrine pancreatic insufficiency. Anaerobe, v. 45, p. 50-58, 2017.
KOOK, Peter H.; ZERBE, P.; REUSCH, Claudia E. Exokrine Pankreasinsuffizienz bei der Katze. Schweiz Arch Tierheilkd, v. 153, p. 19-25, 2011.
LINDKVIST, Björn. Diagnosis and treatment of pancreatic exocrine insufficiency. World Journal of Gastroenterology: WJG, v. 19, n. 42, p. 7258, 2013.
OHMURAYA, Masaki; YAMAMURA, Ken-ichi. The roles of serine protease inhibitor Kazal type 1 (SPINK1) in pancreatic diseases. Experimental animals, v. 60, n. 5, p. 433-444, 2011.
STEINER, Jörg M. Exocrine pancreatic insufficiency in the cat. Topics in companion animal medicine, v. 27, n. 3, p. 113-116, 2012.
SANTOS, Sofia Catarina Jones Pêtas dos. Insuficiência pancreática exócrina em gato. 2017. Tese de Doutorado. Universidade de Lisboa, Faculdade de Medicina Veterinária.
TEFFT, K. M. Exocrine pancreatic insufficiency in dogs and cats. In: Indiana Veterinary Medical Association Annual Meeting. 2015. p. 1-4.
THOMPSON, Kelley A. et al. Feline exocrine pancreatic insufficiency: 16 cases (1992–2007)⋆. Journal of Feline Medicine and Surgery, v. 11, n. 12, p. 935-940, 2009.
TORESSON, Linda et al. Oral cobalamin supplementation in cats with hypocobalaminaemia: a retrospective study. Journal of feline medicine and surgery, v. 19, n. 12, p. 1302-1306, 2017.
XENOULIS, P. G. Diagnosis of pancreatitis in dogs and cats. Journal of small animal practice, v. 56, n. 1, p. 13-26, 2015.
XENOULIS, P. G. et al. Feline exocrine pancreatic insufficiency: a retrospective study of 150 cases. Journal of veterinary internal medicine, v. 30, n. 6, p. 1790-1797, 2016.
WESTERMARCK, Elias; WIBERG, Maria. Exocrine pancreatic insufficiency in the dog: historical background, diagnosis, and treatment. Topics in companion animal medicine, v. 27, n. 3, p. 96-103, 2012.