Nile tilapia skin in the treatment of second-degree burns: a systematic review with meta-analysis
Pele de tilápia do Nilo no tratamento de queimaduras de segundo grau: revisão sistemática com meta-análise
Palavras-chave:
Wound healing, Dressing changes, Nile tilapia skin, Silver-impregnated sodium carboxymethylcellulose, Silver sulfadiazine creamResumo
Objective: Systematically review the effects of using Nile tilapia skin (NTFS) for management/treatment in patients with second-degree skin burns, when compared with two treatments containing silver, hydrofiber dressing or sulfadiazine cream (AgSD). Methodology: Systematic review with meta-analysis performed in january 2023, using PubMed, Web of Science, CINAHL, Scopus, Cochrane and Gale databases, to identify relevant randomized clinical trials. Results: In total, five randomized trials were identified comparing the use of NTFS with two types of silver-based treatment of second-degree skin burns. Occlusive dressings with NTFS significantly reduced pain levels, measured using the Visual Analogue Scale - VAS (p=0.0008), time (measured in days) for complete wound healing, corresponding to re-epithelialization of 95% or more of the initial burn (p=0.002), and the number of dressings needed until complete healing of the burn (p=0.0004). Conclusion: The results confirm the positive effects of using the NTFS dressing on patients with second-degree burns and can benefit public health systems, especially in developing and resource-poor countries.
Downloads
Referências
ABDEL-SAYED, Philippe; HIRT-BURRI, Nathalie; DE BUYS ROESSINGH, Anthony; RAFFOUL, Wassim; APPLEGATE, Lee Ann. Evolution of Biological Bandages as First Cover for Burn Patients. Advances in Wound Care, [S. l.], v. 8, n. 11, p. 555–564, 2019.
ALVES, A. P. N. N. et al. Avaliação microscópica, estudo histoquímico e análise de propriedades tensiométricas da pele de tilápia do Nilo. Revista Brasileira de Queimaduras, [S. l.], v. 14, n. 3, p. 203–210, 2015.
ALVES, Ana Paula Negreiros Nunes et al. Study of tensiometric properties, microbiological and collagen content in nile tilapia skin submitted to different sterilization methods. Cell and Tissue Banking, [S. l.], v. 19, n. 3, p. 373–382, 2018.
AUSTIN, Ryan E.; MERCHANT, Nishant; SHAHROKHI, Shahriar; JESCHKE, Marc G. A comparison of Biobrane™ and cadaveric allograft for temporizing the acute burn wound: Cost and procedural time. Burns, [S. l.], v. 41, n. 4, p. 749–753, 2015.
AZULAY, R. D.; AZULAY, L. Dermatologia. A Pele: Função, Estrutura, Fisiologia e Embriologia. 7. ed. Rio de Janeiro: Guanabara Koogan, 2017.
BARROSO, RM; MUÑOZ, AEP; CAI, J. Social and economic performance of tilapia farming in Brazil. Rome: FAO Fisheries and Aquaculture Circular No. 1181, 2019.
CÁCERES-JEREZ, Luz Elena; GOMEZESE-RIBERO, Omar Fernando; REYES-CÁRDENAS, Laura Isabel; VERA-CAMPOS, Julián Andrés; GUZMÁN-RUEDA, Valentina Alejandra; AZAR-VILLALOBOS, Juan Pablo; MELÉNDEZ-FLÓREZ, Héctor Julio. Management of acute pain in extensive burn injury. Colombian Journal of Anesthesiology, [S. l.], v. 46, n. 1, p. 49–54, 2018.
CARUSO, Daniel M.; FOSTER, Kevin N.; BLOME-EBERWEIN, Sigri A.; TWOMEY, John A.; HERNDON, David N.; LUTERMAN, Arnold; SILVERSTEIN, Paul; ANTIMARINO, Jeffrey R.; BAUER, Gregory J. Randomized Clinical Study of Hydrofiber Dressing With Silver or Silver Sulfadiazine in the Management of Partial-Thickness Burns. Journal of Burn Care & Research, [S. l.], v. 27, n. 3, p. 298–309, 2006.
CASTRO, Rodrigo José Alencar De; LEAL, Plínio Cunha; SAKATA, Rioko Kimiko. Pain management in burn patients. Revista Brasileira de Anestesiologia, [S. l.], v. 63, n. 1, p. 154–158, 2013.
CHEN, Jingjing; GAO, Kaili; LIU, Shu; WANG, Shujun; ELANGO, Jeevithan; BAO, Bin; DONG, Jun; LIU, Ning; WU, Wenhui. Fish Collagen Surgical Compress Repairing Characteristics on Wound Healing Process In Vivo. Marine Drugs, [S. l.], v. 17, n. 1, p. 33, 2019.
DIÓGENES, Ana Kely de Loyola; FECHINE, Francisco Vagnaldo; COSTA, Bruno Almeida; SOARES, Maria Flaviane Araújo do Nascimento; ROCHA, Marina Becker Sales; MORAES FILHO, Manoel Odorico De; LIMA JÚNIOR, Edmar Maciel; VALE, Mariana Lima. Concurrent validity of electronic von Frey as an assessment tool for burn associated pain. Burns, [S. l.], v. 46, n. 6, p. 1328–1336, 2020.
ECHEVARRIA-GUANILO, Maria Elena; DANTAS, Rosana Aparecida Spadoti; FARINA, Jayme Adriano; FABER, A. Wertus; ALONSO, Jordi; RAJMIL, Luis; ROSSI, Lídia Aparecida. Reliability and validity of the Brazilian-Portuguese version of the Burns Specific Pain Anxiety Scale (BSPAS). International Journal of Nursing Studies, [S. l.], v. 48, n. 1, p. 47–55, 2011.
ELMASRY, Moustafa; STEINVALL, Ingrid; THORFINN, Johan; ABBAS, Ashraf H.; ABDELRAHMAN, Islam; ADLY, Osama A.; SJÖBERG, Folke. Treatment of Children With Scalds by Xenografts. Journal of Burn Care & Research, [S. l.], v. 37, n. 6, p. e586–e591, 2016.
FALLAH, Leili Yeke; AHMADI, Abbas; RUCHE, Amaneh Bagheri; TAREMIHA, Ali; SOLTANI, Nazanin; MAFI, Maryam. The effect of early change of skin graft dressing on pain and anxiety among burn patients: a two-group randomized controlled clinical trial. International Journal of Burns and Trauma, [S. l.], v. 9, n. 1, p. 13–18, 2019.
GREENHALGH, David G. Management of Burns. New England Journal of Medicine, [S. l.], v. 380, n. 24, p. 2349–2359, 2019.
HIGGINS, Julian P. T.; THOMAS, James; CHANDLER, Jacqueline; CUMPSTON, Miranda; LI, Tianjing; PAGE, Matthew J.; WELCH, Vivian A. (ORG.). Cochrane Handbook for Systematic Reviews of Interventions. Second Edi ed. [s.l.] : Wiley, 2019.
HIGGINS, Julian PT; SAVOVIĆ, Jelena; PAGE, Matthew J.; STERNE, Jonathan AC. Revised Cochrane risk-of-bias tool for randomized trials (RoB 2), 2019b. p. 72. HU, Zhang; YANG, Ping; ZHOU, Chunxia; LI, Sidong; HONG, Pengzhi. Marine Collagen Peptides from the Skin of Nile Tilapia (Oreochromis niloticus): Characterization and Wound Healing Evaluation. Marine Drugs, [S. l.], v. 15, n. 4, p. 102, 2017.
HULBERT-WILLIAMS, N. J.; HULBERT-WILLIAMS, S. L.; MCILROY, D.; BUNTING, B. Anxiety in recovery from severe burn injury: An experimental comparison. Psychology, Health & Medicine, [S. l.], v. 13, n. 2, p. 162–167, 2008.
IBRAHIM, Ahmed; SOLIMAN, Mahmoud; KOTB, Saber; ALI, Magda M. Evaluation of fish skin as a biological dressing for metacarpal wounds in donkeys. BMC Veterinary Research, [S. l.], v. 16, n. 1, p. 472, 2020.
JUYBARI, Kobra Bahrampour et al. Sex dependent alterations of resveratrol on social behaviors and nociceptive reactivity in VPA-induced autistic-like model in rats. Neurotoxicology and Teratology, [S. l.], v. 81, n. June, p. 106905, 2020.
KOTANIEMI, A.; RISTELI, J.; AHO, K.; HAKALA, M. Increased type I collagen degradation correlates with disease activity in reactive arthritis. Clinical and Experimental Rheumatology, [S. l.], v. 21, n. 1, p. 95–98, 2003.
KRAUTH, David; WOODRUFF, Tracey J.; BERO, Lisa. Instruments for Assessing Risk of Bias and Other Methodological Criteria of Published Animal Studies: A Systematic Review. Environmental Health Perspectives, [S. l.], v. 121, n. 9, p. 985–992, 2013.
LAYCOCK, Helen; VALENTE, Joao; BANTEL, Carsten; NAGY, Istvan. Peripheral mechanisms of burn injury-associated pain. European Journal of Pharmacology, [S. l.], v. 716, n. 1–3, p. 169–178, 2013.
LIMA-JUNIOR, Edmar Maciel; PICOLLO, Nelson Sarto; MIRANDA, Marcelo José Borges De; RIBEIRO, Wesley Lyeverton Correia; ALVES, ANA PAULA NEGREIROS NUNES PARENTE, Guilherme Emilio Ferreira; MORAES-FILHO, Ezequiel Aguiar; ODORICO, Manoel. The use of tilapia skin (Oreochromis niloticus), as an occlusive biological dressing, in the treatment of burn wounds. Revista Brasi leira de Queimaduras., [S. l.], v. 16, n. 1, p. 10–17, 2017.
LIMA JÚNIOR, Edmar Maciel et al. Innovative Burn Treatment Using Tilapia Skin as a Xenograft: A Phase II Randomized Controlled Trial. Journal of Burn Care & Research, [S. l.], v. 41, n. 3, p. 585–592, 2020.
LIMA JÚNIOR, Edmar Maciel et al. Pediatric Burn Treatment Using Tilapia Skin as a Xenograft for Superficial Partial-Thickness Wounds: A Pilot Study. Journal of Burn Care & Research, [S. l.], v. 41, n. 2, p. 241–247, 2020.
LIMA JÚNIOR, Edmar Maciel et al. A Randomized Comparison Study of Lyophilized Nile Tilapia Skin and Silver-Impregnated Sodium Carboxymethylcellulose for the Treatment of Superficial Partial-Thickness Burns. Journal of Burn Care & Research, [S. l.], v. 42, n. 1, p. 41–48, 2021.
LIMA JÚNIOR, Edmar Maciel et al. Nile Tilapia Fish Skin–Based Wound Dressing Improves Pain and Treatment-Related Costs of Superficial Partial-Thickness Burns: A Phase III Randomized Controlled Trial. Plastic & Reconstructive Surgery, [S. l.], v. 147, n. 5, p. 1189–1198, 2021.
LIMA JUNIOR, Edmar Maciel; BANDEIRA, Tereza de Jesus Pinheiro Gomes; MIRANDA, Marcelo José Borges De; FERREIRA, Guilherme Emilio; PARENTE, Ezequiel Aguiar; PICCOLO, Nelson Sarto; DE MORAES FLHO, Manoel Odorico. Characterization of the microbiota of the skin and oral cavity of Oreochromis niloticus. Journal of Health & Biological Sciences, [S. l.], v. 4, n. 3, p. 193–197, 2016.
MACLEOD, Malcolm R. et al. Risk of Bias in Reports of In Vivo Research: A Focus for Improvement. PLOS Biology, [S. l.], v. 13, n. 10, p. e1002273, 2015. Public Library of Science.
MAGALHÃES, Lucas Moura; RAMIRES, Nadine Tessari; ZUPPA, Carina. Os benefícios da pele de tilápia em pacientes com queimaduras. Revista Multidisciplinar em Saúde, [S. l.], v. 1, n. 3, p. 44, 2020.
MARKIEWICZ-GOSPODAREK, Agnieszka; KOZIOŁ, Małgorzata; TOBIASZ, Maciej; BAJ, Jacek; RADZIKOWSKA-BÜCHNER, Elżbieta; PRZEKORA, Agata. Burn Wound Healing: Clinical Complications, Medical Care, Treatment, and Dressing Types: The Current State of Knowledge for Clinical Practice. International Journal of Environmental Research and Public Health, [S. l.], v. 19, n. 3, p. 1338, 2022.
MARTINEZ, José Eduardo; GRASSI, Daphine Centola; MARQUES, Laura Gasbarro. Análise da aplicabilidade de três instrumentos de avaliação de dor em distintas unidades de atendimento: ambulatório, enfermaria e urgência. Revista Brasileira de Reumatologia, [S. l.], v. 51, n. 4, p. 299–308, 2011.
MAY, Andrew; KOPECKI, Zlatko; CARNEY, Bernard; COWIN, Allison. Antimicrobial silver dressings: a review of emerging issues for modern wound care. ANZ Journal of Surgery, [S. l.], v. 92, n. 3, p. 379–384, 2022.
MIRANDA, Marcelo José Borges De. Viabilidade da pele de Tilápia do Nilo (Oreochromis niloticus) como curativo biológico no tratamento de queimaduras: revisão da literatura. Anais da Faculdade de Medicina de Olinda, [S. l.], v. 1, n. 1, p. 49–52, 2018.
MIRANDA, M. J. B.; BRANDT, C. T. Nile tilapia skin xenograft versus silver-based hydrofiber dressing in the treatment of second-degree burns in adults. Brazilian Journal of Plastic Sugery, [S. l.], v. 34, n. 1, p. 79–85, 2019.
NAJAFI GHEZELJEH, T.; MOHADES ARDEBILI, F.; RAFII, F. The effects of massage and music on pain, anxiety and relaxation in burn patients: Randomized controlled clinical trial. Burns, [S. l.], v. 43, n. 5, p. 1034–1043, 2017.
NOGUEIRA, Beatriz Lima; DA SILVA, Mariana Leite Rosa Pinheiro; DA CRUZ, Silvia Helena; DE ALMEIDA, Ana Claudia Correa; DE BITTENCOURT, Renata Aparecida. Os curativos a base de prata e sua eficácia em queimaduras: uma revisão integrativa / Silver-based dressings and their effectiveness in burns: an integrative review. Brazilian Journal of Development, [S. l.], v. 8, n. 2, p. 8535–8556, 2022.
PAGE, Matthew J. et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ, [S. l.], v. 372, p. n71, 2021.
PINA, Tainá de Vasconcelos; ROCHA, Priscilla Roberta Silva. What do we know about the use of Tilapia skin in wound healing? integrative review. Brazilian Journal of Health Review, [S. l.], v. 4, n. 4, p. 16302–16316, 2021.
PIPELZADEH, Mahsa; SIAHPOOSH, Amir; SHEIKHI, Abdul Reza; JAFARZADEH, Elham. Effectiveness of green tea cream in comparison with silver sulfadiazine cream in the treatment of second degree burn in human subjects. Journal of Herbal Medicine, [S. l.], v. 32, p. 100533, 2022.
RETROUVEY, Helene; SHAHROKHI, Shahriar. Pain and the Thermally Injured Patient—A Review of Current Therapies. Journal of Burn Care & Research, [S. l.], v. 36, n. 2, p. 315–323, 2015.
RICHARDSON, P.; MUSTARD, L. The management of pain in the burns unit. Burns, [S. l.], v. 35, n. 7, p. 921–936, 2009.
TENA, Beatriz; ESCOBAR, Bibiana; ARGUIS, M. Jose; CANTERO, Cristina; RIOS, Jose; GOMAR, Carmen. Reproducibility of Electronic von Frey and von Frey Monofilaments Testing. The Clinical Journal of Pain, [S. l.], v. 28, n. 4, p. 318–323, 2012.
WANG, Yuwei; WU, Bohan; MA, Shu; WANG, Duming; GAN, Tian; LIU, Hongyan; YANG, Zhen. Effect of mapping characteristic on audiovisual warning: Evidence from a simulated driving study. Applied Ergonomics, [S. l.], v. 99, p. 103638, 2022.
ZHOU, Tian; WANG, Nanping; XUE, Yang; DING, Tingting; LIU, Xin; MO, Xiumei; SUN, Jiao. Electrospun tilapia collagen nanofibers accelerating wound healing via inducing keratinocytes proliferation and differentiation. Colloids and Surfaces B: Biointerfaces, [S. l.], v. 143, p. 415–422, 2016.
