Clinical-epidemiological profile of COVID-19 and its relationship with chronic diseases in the state of Pernambuco/Brazil
Perfil clínico-epidemiológico da COVID-19 e sua relação com as doenças crônicas no estado de Pernambuco/Brasil
Palavras-chave:
COVID-19, Comorbidity, PernambucoResumo
Objective: To analyze the clinical-epidemiological and laboratory profile of COVID-19 and the relationship with chronic diseases in Pernambuco/Brazil. Methodology: Descriptive and analytical study of the population affected by COVID-19, in Pernambuco, between 08/28-18/11/2020. Results: There was a prevalence of COVID-19 between 31 and 60 years (p<0.0001); with higher records in Health Units (E-SUS) for women (57.58%; p<0.0001) and Emergency Care (F-SUS) for men (51.73%; p<0.0001). Among symptomatic patients in the E-SUS, cough (26.2%), fever (22.3%) and odynophagia (19.4%) prevailed - mild profile (78.5%; p<0.0001); and, in the F-SUS, saturation <95% (36.3%) and dyspnea (28.6%) - severe profile (63.8%; p<0.0001). In clinical evolution, patients under 60 years of age had a favorable outcome in the absence of comorbidities (79.6%; p<0.0001); in those over 60 years of age, the outcome was death among those without comorbidity (61.2%; p0.0083), two comorbidities (72.9%; p0.0001), three or more comorbidities (81.8%; p0.0005) and for cardiovascular diseases (63.6%; p0.0036). Conclusion: It was possible to observe a distinct clinical profile between E-SUS and F-SUS care, and vulnerability in >60 years with or without comorbidity.
Keywords: COVID-19; Comorbidity; Pernambuco
Downloads
Referências
AQUINO, Estrela Leite et al. Social distancing measures in the control of the COVID-19 pandemic: potential impacts and challenges in Brazil. Ciência & Saúde Coletiva 2020.
BRANDÃO, Simone Cristina Soares et al. Role of immunometabolism, Toll-Like receptors and ACE 2 in COVID-19. Arquivos de Asma, Alergia e Imunologia, v.5, n. 1, p.66-78, 2021.
BRAZ, Leonardo Graco de Oliveira et al. Gender expressions in the process of care and prevention of COVID-19 during the pandemic: reflections from and for social occupational therapy. Cadernos Brasileiros de Terapia Ocupacional. 2022.
BRAZIL. Ministry of Health. Symptoms [Internet]. Ministry of Health, 2021
CAI, Jie Hao et al. A case series of children with 2019 novel coronavirus infection: clinical and epidemiological features. Clinical Infectious Diseases. V. 28, N. 71, 2020.
CERQUEIRA, Selma Regina Penha et al. The Risk of SARS-CoV-2 Infection in Patients with Leprosy and their Contact Persons: A Prospective Cohort Study. Brasília: Faculty of Medicine, University of Brasília, 2021.
DATTNER, Itai et al. The role of children in the spread of COVID-19: Using household data from Bnei Brak, Israel, to estimate the relative susceptibility and infectivity of children. Lloyd-Smith J, editor. PLOS Computational Biology. 2021.
FISCHER, Liu. Unraveling the Mystery of Why Children Are Better Protected from COVID Than Adults. Scientific American, 2023.
GIOVANELLA, Ligia et al. National Primary Care Policy: where are we going? Ciência & Saúde Coletiva, v.25, n. 4, p. 1475-82, 2020.
GOVERNMENT OF THE STATE OF PERNAMBUCO. DECREE No 48.809; 48.833, 2020.
HOPKINS, Chan et al. N. Presentation of new onset anosmia during the COVID-19 pandemic. Rhinology, v. 58, n. 3, p. 295-298, 2020.
HOU, Hongyan et al. Detection of IgM and IgG antibodies in patients with coronavirus disease 2019. Clinical & Translational Immunology, 2020.
IZCOVICH, Ariel et al. Prognostic factors for severity and mortality in patients infected with COVID-19: A systematic review. Lazzeri C, editor. PlosOne. 2020.
KLOPFENSTEIN, Then et al. Features of anosmia in COVID-19. Médecine et Maladies Infectieuses. V. 50, n. 5, 2020.
LOTTA, Gabriela L et al. How COVID-19 Has Affected Frontline Workers in Brazil: A Comparative Analysis of Nurses and Community Health Workers. Journal of Comparative Policy Analysis: Research and Practice, v. 5, n. 23, p.63-73, 2020
MELO, José Romério Rabelo et al. Adverse drug reactions in COVID-19 patients in Brazil: analysis of spontaneous notifications from the Brazilian pharmacovigilance system. Cadernos de Saúde Pública, v. 37, n. 1, 2021.
NEIVA, Neiva, Mariane et al. Brazil: the emerging epicenter of COVID-19 pandemic. Revista da Sociedade Brasileira de Medicina Tropical, n. 53, 2020.
MESENBURG, Marilia et al. Chronic non-communicable diseases and COVID-19: EPICOVID-19 Brazil results. Revista de Saúde Pública, n.55, p.1-11, 2021.
SANTOS, André Luiz Pinto et al. Analysis and forecast of the evolution of the number of deaths by COVID-19 in the state of Pernambuco and Ceará using regression models. RSD, 2020.
SILVA, Rosalva Raimundo et al. The internalization of covid-19 in the municipalities of the state of Pernambuco, northeastern Brazil. Brazilian Journal of Maternal and Child Health, 2021.
SILVA, Eliane Oliveira et al. Epidemiological profile of COVID-19 cases in the VIII health region of Pernambuco, Brazil. Revista de Saúde Coletiva da UEFS, v.12, n.1, 2022.
SINGHAL, Tanu. A Review of Coronavirus Disease-2019. In Indian Journal of Pediatrics, 2020.
YZDANPANAHA, Fereshteh et al. The immune system and COVID-19: Friend or foe? LS, 2020.
ZÚÑIGA, Milton Rodríguez et al. Factores de riesgo asociados a mortalidad en pacientes adultos con neumonía por SARS-CoV-2 en un hospital público de Lima, Perú. Acta Med, 2020.
