Epidemiology of schistosomiasis in Brazil: a retrospective study
Epidemiologia da esquistossomose no Brasil: um estudo retrospectivo
Palavras-chave:
Schistosomiasis, Epidemiology, Public Health SurveillanceResumo
Schistosomiasis is a parasitic disease caused by the trematode Schistosoma mansoni, whose adult forms inhabit the mesenteric vessels of the definitive host (man) and the intermediate forms develop in aquatic gastropod snails of the genus Biomphalaria. The objective of this study was to analyze the cases of Schistosomiasis in Brazil, from 2012 to 2022. The methodology used for the descriptive and retrospective study on the cases of Schistosomiasis was the analysis of data from the Information System for Notifiable Diseases (Sinan) /Datasus, recorded from 2012 to 2022. The main results were the 50,687 records of disease notifications, with an annual average of 4,607.90 cases and 67.09 deaths. The Southeast and Northeast macro-regions were responsible for the highest number of cases per year. Most of the notified infections occurred in brown (56%) and white (31%) races. Schistosomiasis is an emerging and prevalent zoonosis in Brazil, and it is important to implement more effective interventionist public policies for the prevention and control of the disease.
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BAIS, S.; GREENBERG, R. M. TRP channels as potential targets for antischistosomals. International Journal for Parasitology: Drugs and Drug Resistance, v. 8, n. 3, p. 511–517, dez. 2018.
CIMERMAN, B.; CIMERMAN, S. Parasitologia humana: e seus fundamentos gerais. 2. ed. São Paulo: Atheneu, 2018.
FAUST, C.L. et al. Schistosomiasis Control: leave no age group behind. Trends In Parasitology, [S.L.], v. 36, n. 7, p. 582-591, jul. 2020. Elsevier BV. http://dx.doi.org/10.1016/j.pt.2020.04.012.
HOLANDA, E.C. et al. Caracterização epidemiológica e prevalência de esquistossomose no Estado do Maranhão, Brasil. Research, Society and Development, v. 9, n. 8, 2020.
KOVAČ, J. et al. Pharmacokinetics of Praziquantel in Schistosoma mansoni- and Schistosoma haematobium-Infected School- and Preschool-Aged Children. Antimicrobial Agents and Chemotherapy, v. 62, n. 8, 4 jun. 2018.
SOBRINHO, F.S.L. et al. Incidência de Esquistossomose Mansônica no Nordeste brasileiro, no período de 2013 a 2017. Diversitas Journal, [S.L.], v. 5, n. 4, p. 2881-2889, 27 out. 2020. http://dx.doi.org/10.17648/diversitas-journal-v5i4-984.
MCMANUS, D.P. et al. Schistosomiasis—from immunopathology to vaccines. Seminars In Immunopathology, [S.L.], v. 42, n. 3, p. 355-371, 19 fev. 2020. Springer Science and Business Media LLC. http://dx.doi.org/10.1007/s00281-020-00789-x.
MINISTÉRIO DA SAÚDE. Vigilância da Esquistossomose Mansoni: diretrizes técnicas, Brasília, 4 ed., 2014.
MINISTÉRIO DA SAÚDE. Esquistossomose: Manejo clínico e epidemiológico na atenção básica, Recife, 2017b.
MINISTÉRIO DA SAÚDE. Nota Informativa Nº 11, de 2017/CGHDE/DEVIT/SVS/MS. Orientações sobre o diagnóstico e tratamento da esquistossomose mansoni nas unidades de saúde, Brasília, 2017a.
MINISTÉRIO DA SAÚDE. Guia de Vigilância em Saúde, Brasília, 3 ed., 2019.
MOLEHIN, Adebayo J. Schistosomiasis vaccine development: update on human clinical trials. Journal Of Biomedical Science, [S.L.], v. 27, n. 1, p. 1-7, 22 Jan. 2020.. http://dx.doi.org/10.1186/s12929-020-0621-y.
NEVES, David Pereira. Parasitologia humana. 13. ed. São Paulo : Editora Atheneu, 2016.
PAZ, W.S. et al. Basic and associated causes of schistosomiasis-related mortality in Brazil: a population-based study and a 20-year time series of a disease still neglected. Journal Of Global Health, [S.L.], v. 11, p. 1-12, 9 out. 2021. International Global Health Society. http://dx.doi.org/10.7189/jogh.11.04061.
PEREIRA, G.S., OLIVEIRA, H.M.B.F., OLIVEIRA FILHO, A. A. (2018). Educação ambiental em saúde: análise dos casos de esquistossomose notificados na paraíba no período de 2015 A 2017. Educação Ambiental em Ação, 17(64)
PINHEIRO, M.C.C. et al. Burden of schistosomiasis‐related mortality in Brazil: epidemiological patterns and spatial⠳temporal distribution, 2003-2018. Tropical Medicine & International Health, [S.L.], v. 25, n. 11, p. 1395-1407, 5 out. 2020. Wiley. http://dx.doi.org/10.1111/tmi.13483.
SÁNCHEZ-MARQUÉS, R. et al. Research on Schistosomiasis in the Era of the COVID-19 Pandemic: a bibliometric analysis. International Journal Of Environmental Research And Public Health, [S.L.], v. 19, n. 13, p. 8051, 30 jun. 2022. MDPI AG. http://dx.doi.org/10.3390/ijerph19138051
SANTOS, J.P.N. et al. Caracterização do perfil epidemiológico da esquistossomose no nordeste brasileiro. In:CONGRESSO NACIONAL DE ENFERMAGEM-CONENF, 2018, Sergipe. Anais CONENF.p. 1-1.
SCHNEEBERGER, P. H. H. et al. Investigations on the interplays between Schistosoma mansoni, praziquantel and the gut microbiome. Parasites & Vectors, v. 11, 12 mar. 2018.
SILVA, B.M. et al. High schistosomiasis-related mortality in Northeast Brazil: trends and spatial patterns. Revista da Sociedade Brasileira de Medicina Tropical, [S.L.], v. 55, p. 1-8, 2022. FapUNIFESP (SciELO). http://dx.doi.org/10.1590/0037-8682-0431-2021.
SILVA, Lucas Emanuel de Oliveira; WANDERLEY, Flaviana Santos. Análise do Programa de Controle da Esquistossomose na redução dos indicadores epidemiológicos da doença no Brasil, de 1995 a 2017. Revista Pan-Amazônica de Saúde, [S.L.], v. 13, n. 9, p. 1-9, jun. 2022. http://dx.doi.org/10.5123/s2176-6223202200956.
VALE, N. et al. Praziquantel for Schistosomiasis: Single-Drug Metabolism Revisited, Mode of Action, and Resistance. Antimicrobial Agents and Chemotherapy, v. 61, n. 5, 6 mar. 2017.
WILSON, R.A. Schistosomiasis then and now: what has changed in the last 100 years? Parasitology, p. 1–9, 22 jan. 2020.
