Malaria: a historical, eminent and persistent problem

Malária: um problema histórico, eminente e persistente

Autores

Palavras-chave:

Plasmodium, Africa, Vaccine, Public health

Resumo

The sub-Saharan Africa region concentrates more than 90% of notifications of malaria infections. However, the disease is not concentrated only in the African continent, being endemic even in the Amazon region of Brazil. Thus, it is imperative that there are effective actions to mitigate and eradicate the disease. In this sense, a bibliometric analysis was carried out to address current facts related to the characterization of the parasite, vector control, disease diagnosis and treatment of patients. The results indicate that methods for vector control, although effective, are not available for the entire population of endemic countries and their effectiveness has been circumvented by the vector over time. Chemical treatments with antimalarials also suffer from acquired resistance by the pathogen. Furthermore, the most current therapy is the developed and tested anti-malarial vaccine, with results that proved to be viable in economic and public health terms. In view of the high number of deaths caused by malaria, especially in children living in areas of high contagion, the World Health Organization has started to recommend the use of this resource, which could save thousands of lives every year.

Downloads

Não há dados estatísticos.

Biografia do Autor

Ubiratan Alegransi Bones, Universidade Federal de Santa Maria

Mestrando do Programa de Pós-graduação em Ciência e Tecnologia Ambiental – UFSM

Genesio Mario da Rosa, Universidade Federal de Santa Maria

Prof. Dr. Titular da Universidade Federal da Santa Maria

Kauane Andressa Flach, Universidade Federal de Santa Maria

Doutoranda em Engenharia Ambiental da UFSM

Jefferson Alves da Costa Junior, Universidade Federal de Santa Maria

Prof. Dr. Adjunto da Universidade Federal da Santa Maria

Mathias Rezende Mahnke, Universidade Federal de Santa Maria

Graduando em Agronomia na Universidade Federal da Santa Maria

Referências

ADAMS, John H.; MUELLER, Ivo. The biology of Plasmodium vivax. Cold Spring Harbor perspectives in medicine, 2017, 7.9: a025585.

ANSARI, Hifzur Rahman, et al. Genome-scale comparison of expanded gene families in Plasmodium ovale wallikeri and Plasmodium ovale curtisi with Plasmodium malariae and with other Plasmodium species. International journal for parasitology, 2016, 46.11: 685-696.

ANSTEY, Nicholas M. et al. Plasmodium vivax: clinical spectrum, risk factors and pathogenesis. Advances in parasitology, v. 80, p. 151-201, 2012.

BAIRD, J. Kevin. Evidence and implications of mortality associated with acute Plasmodium vivax malaria. Clinical microbiology reviews, 2013, 26.1: 36-57.

BANYATSUPPASIN, Wansa, et al. Prevalence of thalassemia and glucose-6-phosphate dehydrogenase deficiency in newborns and adults at the Ramathibodi Hospital, Bangkok, Thailand. Hemoglobin, 2017, 41.4-6: 260-266.

BARBER, Bridget E., et al. Clinical management of Plasmodium knowlesi malaria. Advances in parasitology, 2021, 113: 45-76.

BEESON, J. G.; BROWN, G. V. Pathogenesis of Plasmodium falciparum malaria: the roles of parasite adhesion and antigenic variation. Cellular and Molecular Life Sciences CMLS, 2002, 59: 258-271.

BOUCHAUD, Olivier. Malaria prevention. La Revue du Praticien, 2019, 69.2: 166-170.

BRASIL, Ministério da Saúde. Situação Epidemiológica da Malária. 2023. Disponível em:https://www.gov.br/saude/pt-br/assuntos/saude-de-a-a-z/m/malaria/situacao-epidemiologica-da-malaria-1#:~:text=De%20acordo%20com%20a%20Organiza%C3%A7%C3%A3o,2020%20para%20619.000%20em%202021.Acesso em: 16 mar. 2023.

CDC, Centers For Disease Control And Prevention. Malaria’s Impact Worldwide: global health, division of parasitic diseases and malaria. Global Health, Division of Parasitic Diseases and Malaria. 2021. Disponível em: https://www.cdc.gov/malaria/malaria_worldwide/impact.html. Acesso em: 16 mar. 2023.

CENTERS FOR DISEASE CONTROL AND PREVENTION, et al. CDC-Malaria-Diagnosis & Treatment (United States)-Treatment (US). Centers for Disease Control and Prevention. https://www. cdc. gov/malaria/diagnosis_treatment/treatment. html, 2020.

CDC. Malaria vaccine recommended for broader use by WHO: “Best thing since bed nets”. 2023. Disponível em: https://www.cdc.gov/parasites/features/malaria_vaccine_who.html. Acesso em: 17 mar. 2023.

CHAUVET, Margaux, et al. Sickle cell trait modulates the proteome and phosphoproteome of Plasmodium falciparum-infected erythrocytes. Frontiers in Cellular and Infection Microbiology, 2021, 11: 637604.

COLLINS, William E.; JEFFERY, Geoffrey M. Plasmodium malariae: parasite and disease. Clinical microbiology reviews, v. 20, n. 4, p. 579-592, 2007.

COSTA, Fabio et al. On cytoadhesion of Plasmodium vivax: raison d'être?. Memórias do Instituto Oswaldo Cruz, v. 106, p. 79-84, 2011.

CULLETON, Richard; PAIN, Arnab; SNOUNOU, Georges. Plasmodium malariae: the persisting mysteries of a persistent parasite. Trends in Parasitology, 2022.

DAILY, Johanna P.; MINUTI, Aurelia; KHAN, Nazia. Diagnosis, treatment, and prevention of malaria in the US: a review. JAMA, 2022, 328.5: 460-471.

DAS BS. 2008. Renal failure in malaria. J Vector Borne Dis 45: 83–97.

FEACHEM, Richard GA, et al. Malaria eradication within a generation: ambitious, achievable, and necessary. The Lancet, 2019, 394.10203: 1056-1112.

GALINSKI, Mary R.; BARNWELL, John W. Plasmodium vivax: who cares?. Malaria journal, v. 7, n. 1, p. 1-18, 2008.

GARRIDO-CARDENAS, José Antonio, et al. Plasmodium genomics: an approach for learning about and ending human malaria. Parasitology research, 2019, 118: 1-27.

GONÇALVES, Raquel Müller; LIMA, Nathália Ferreira; FERREIRA, Marcelo Urbano. Parasite virulence, co-infections and cytokine balance in malaria. Pathogens and global health, v. 108, n. 4, p. 173-178, 2014.

GRAU, Georges Emile Raymond; CRAIG, Alister Gordon. Cerebral malaria pathogenesis: revisiting parasite and host contributions. Future microbiology, v. 7, n. 2, p. 291-302, 2012.

IMWONG, Mallika, et al. The epidemiology of subclinical malaria infections in South-East Asia: findings from cross-sectional surveys in Thailand–Myanmar border areas, Cambodia, and Vietnam. Malaria journal, 2015, 14.1: 1-13.

KRZYCH, Urszula; ZARLING, Stasya; PICHUGIN, Alexander. Memory T cells maintain protracted protection against malaria. Immunology letters, v. 161, n. 2, p. 189-195, 2014.

MBANEFO, Evaristus Chibunna, et al. Association of glucose-6-phosphate dehydrogenase deficiency and malaria: a systematic review and meta-analysis. Scientific reports, 2017, 7.1: 45963.

MILNER JR, Danny A. et al. Transcriptional profiling of Plasmodium falciparum parasites from patients with severe malaria identifies distinct low vs. high parasitemic clusters. PloS one, v. 7, n. 7, p. e40739, 2012.

MILNER, Danny A. Malaria pathogenesis. Cold Spring Harbor perspectives in medicine, 2018, 8.1: a025569.

MORENO‐PÉREZ, Darwin A.; RUÍZ, Jhenniffer A.; PATARROYO, Manuel A. Reticulocytes: Plasmodium vivax target cells. Biology of the Cell, v. 105, n. 6, p. 251-260, 2013.

MUELLER, Ivo; ZIMMERMAN, Peter A.; REEDER, John C. Plasmodium malariae and Plasmodium ovale–the ‘bashful’malaria parasites. Trends in parasitology, 2007, 23.6: 278-283.

MÜLLER, Mattia; SCHLAGENHAUF, Patricia. Plasmodium knowlesi in travellers, update 2014. International Journal of Infectious Diseases, v. 22, p. 55-64, 2014.

NDOUR, Papa Alioune, et al. Measuring the Plasmodium falciparum HRP2 protein in blood from artesunate-treated malaria patients predicts post-artesunate delayed hemolysis. Science translational medicine, 2017, 9.397: eaaf9377.

OAKLEY, Miranda S. et al. Clinical and molecular aspects of malaria fever. Trends in parasitology, v. 27, n. 10, p. 442-449, 2011.

OGUIKE, Mary Chiaka et al. Plasmodium ovale curtisi and Plasmodium ovale wallikeri circulate simultaneously in African communities. International journal for parasitology, v. 41, n. 6, p. 677-683, 2011.

OPS, Organización Panamericana de La Salud. Malaria. 2018. Disponível em: https://www.paho.org/es/temas/malaria. Acesso em: 17 mar. 2023.

ORIERO, Eniyou C., et al. Plasmodium malariae, current knowledge and future research opportunities on a neglected malaria parasite species. Critical reviews in microbiology, 2021, 47.1: 44-56.

PLEWES, Katherine, et al. Malaria: what’s new in the management of malaria?. Infectious Disease Clinics, 2019, 33.1: 39-60.

RAJAGOPALAN A, ILBOUDO CM. Malaria. Pediatr Rev. 2019 Mar;40(3):151-153. doi: 10.1542/pir.2017-0225. Epub 2019 Mar 1. PMID: 30824502.

RTS, S. C. T. P. Efficacy and safety of RTS, S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial. The Lancet, 2015, 386.9988: 31-45.

RUTLEDGE, Gavin G. et al. Plasmodium malariae and P. ovale genomes provide insights into malaria parasite evolution. Nature, v. 542, n. 7639, p. 101-104, 2017.

SCHELLENBERG, David et al. African children with malaria in an area of intense Plasmodium falciparum transmission: features on admission to the hospital and risk factors for death. The American journal of tropical medicine and hygiene, v. 61, n. 3, p. 431-438, 1999.

SINGH, Balbir; DANESHVAR, Cyrus. Human infections and detection of Plasmodium knowlesi. Clinical microbiology reviews, v. 26, n. 2, p. 165-184, 2013.

SITPRIJA, Visith, et al. Renal failure in malaria. The Lancet, 1967, 289.7483: 185-188.

SMITH, Joseph D. et al. Malaria's deadly grip: cytoadhesion of P lasmodium falciparum‐infected erythrocytes. Cellular microbiology, v. 15, n. 12, p. 1976-1983, 2013.

STONE, Will et al. Assessing the infectious reservoir of falciparum malaria: past and future. Trends in parasitology, v. 31, n. 7, p. 287-296, 2015.

TWOHIG, Katherine A. et al. Growing evidence of Plasmodium vivax across malaria-endemic Africa. PLoS neglected tropical diseases, v. 13, n. 1, p. e0007140, 2019.

VISSER, B. Jelle, et al. The treatment of malaria. Nederlands Tijdschrift Voor Geneeskunde, 2019, 163.

WASSMER, Samuel C., et al. Investigating the pathogenesis of severe malaria: a multidisciplinary and cross-geographical approach. The American journal of tropical medicine and hygiene, 2015, 93.3 Suppl: 42.

WEATHERALL, D. J. Genetic variation and susceptibility to infection: the red cell and malaria. British journal of haematology, v. 141, n. 3, p. 276-286, 2008.

WHITE, N. J., et al. Malaria. Lancet [Internet]. 2014; 383 (9918): 723–35.

WHITE, Nicholas J. Anaemia and malaria. Malaria journal, 2018, 17.1: 1-17.

WHO, World Healt Organization. Countries and territories certified malaria-free by WHO. 2021. Disponível em: https://www.who.int/teams/global-malaria-programme/elimination/countries-and-territories-certified-malaria-free-by-who. Acesso em: 17 mar. 2023.

WHO, WORLD HEALTH ORGANIZATION et al. World malaria report 2014: summary. World Health Organization, 2015.

WHO, World Health Organization. Malaria. 2022. Disponível em: https://www.who.int/news-room/fact-sheets/detail/malaria. Acesso em: 16 mar. 2023.

WHO, World Health Organization. Message by the Director of the Department of Immunization, Vaccines and Biologicals at WHO - March 2023. 2023. Disponível em: https://www.who.int/news/item/14-03-2023-message-by-the-director-of-the-department-of-immunization--vaccines-and-biologicals-at-who---march-2023. Acesso em: 17 mar. 2023.

WILLYARD, Cassandra, et al. The slow roll-out of the world’s first malaria vaccine. Nature, 2022, 612.7941: 48-49.

WORLD HEALTH ORGANIZATION, et al. World malaria report 2022. World Health Organization, 2022.

ZEKAR, L.; SHARMAN, T. Plasmodium Falciparum Malaria. [Updated 2022 Aug 8]. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing, 2022.

ZIMMERMAN, Peter A. et al. Red blood cell polymorphism and susceptibility to Plasmodium vivax. Advances in parasitology, v. 81, p. 27-76, 2013.

Publicado

2023-04-27

Edição

Seção

Articles